Thalidomide

Thalidomide is a sedative-hyp nonic do medicates which was first released to the public in 1957. It was utilize mostly by pregnant women as a dormancy pill, because it alike possessed the benefits of preventing morning sickness (Spiegel). In the 1950s, naught had ever considered that thalidomide may possess DNA-altering properties (Hirsch). The long-term make that thalidomide has on the body and fetuses prove to be catastrophic, however, it unquestionably has overconfident uses today. Thalidomide was actual by a German pharmaceutical association called Grunenthal in 1953. It was accidentally discovered during the development of a sleazy antibiotic. When the connection discovered Thalidomides soporific properties, it was soon marketed as a sedative, with little investigation as to its adverse loading (Thalidomide Victims). In addition to its sedative effectuate on the gay body, it was also proven to prevent nausea, making it a customary drug for pregnant wo men, as it prevented morning sickness and helped them to revert sleepyheaded at night. What was not known about the drug, however, was that it is a teratogen, or a drug that harms fetal development (Spiegel). When tested in animals, the chemical seemed to be harmless; high doses did not terms the animals.

As a result, the German scientists considered thalidomide to be nonvenomous(Hirsch). However, what the scientists did not acknowledge was that thalidomide did not display tranquilizing effects on the animals. Had they taken this into consideration, they would have realized that not however does the drug not harm animals, but it has no effect on the animals! at allneither negative nor positive. near 10,000 children were innate(p) with severe birth defects between the years of 1956 and 1962, as a result of women taking thalidomide during their pregnancies. Of the 10, 000 children with thalidomide birth defects known; whole cardinal were born in the United States. This is because FDA medical referee Dr. Francis Kelsey blocked...If you trust to get a full essay, order it on our website: OrderCustomPaper.com

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